Could you have this backwards? Maybe retroviruses come from designed-in variation inducing genetic elements (VIGEs)?

URL: https://barryhisblog.blogspot.com/p/could-you-have-this-backwards.html

Acronyms sound so 'sciency', don't they? "DNA", "RNA", "CMBR", "SARS" etc. You can find them throughout the scientific literature. But "VIGE"? It only appears in creationist and cdesign proponentsist literature. It's an example of cargo cult science. Trying to sound sciencey when you have no evidence or reason to support your nutty ideas is an indicative feature of pseudo-science.



Simplified representation of the life cycle of a retrotransposon from Wikipedia





Many creationists/cdesign proponentsists have clutched at this idea to attempt to cast doubt on the conclusion that ERVs are the inherited remnants of retroviral integrations.

The idea is that some god or other "intelligent designer" poofed or designed (as appropriate) these elements in organisms in order to make them 'roll the dice' and re-integrate DNA into other regions of the genome either by direct DNA->RNA>DNA transcription and retrotranscription, or by the less direct route of creating exogenous retroviruses that may then re-integrate into the genome.

There are several basic problems with this idea.

1) There is no evidence for them being originally poofed-or-designed-in elements. A basic guiding principle of science is that of parsimony. You do not complicate your ideas in the absence of evidence. It is unnecessary. And a tedious waste of time.

2) There is no means of distinguishing between the mooted 'VIGEs' and their re-integrated products.

3) Whatever the answer to 2), their products still appear in corresponding loci in related species, and still force us to conclude common ancestry for the reasons already explained at length in this FAQ. 

4) Why would a god or other "intelligent designer'" employ such a hit-and-miss method of distributing copies of genetic material, for all intents and purposes at random in the genomes they created, more often than not causing damage?

5) Why are none of these so-called "VIGEs" still active in the population?

6) Why couldn't this god or other "intelligent" designer just poof or design in what they wanted in the first place?

7) The whole idea of the utility of "variation inducing genetic elements" is highly derivative of the principle of the natural selection of undirected heritable variations. Either this principle is valid, or it is not. You can't have it both ways.

8) According to creationist lore, "information cannot increase in the genome", yet here they are, proposing a mechanism to do just that.

See also, "The 'Not Junk' Anti-ERV Defence"
and "But how can you rule out design as an explanation?"

From https://barryhisblog.blogspot.com/p/endogenous-retroviruses-frequently.html

2 comments:

  1. thats exactly right ERVs come from design . the fact that some show common ancestry only confirms that some species are more like other species, which is found throughout all the different species on earth, AND IN NO WAY DOES IT PROVE THAT THESE SPECIES, ALTHOUGH SIMILAR IN DNA, were the result of one common ancestor evolving into the other species in fact, if that were the case, then considering all the different species, at least 1/3 of the fossils in the fossil record would be transitional fossils showing the in between species, the species as it was evolving from common ancestor into the present species, but there isnt 1/3 of the fossils showing this, lol lol lol whats more there isnt even ONE fossil that shows this change. this lames whole argument is just nonsense. and on. top of that, the creator of this blog, he couldnt answer even the first thing about DNA without the help of AI which is where he generates every answer he posts. none of it. comes from his own understanding or knowledge of the topics hes challenging. dude did not even understand what was meant when i said that no change happens outside any one species own kind. when i said that he said, whatever thats supposed to mean. i said it means that dogs are still dogs, horses still horses, no matter how much adaption takes place no matter how much change occurs the within species dna, it has never caused the change create a different species, and this species is determined by its ability to breed within its own kind, he says, what is that suposed to mean or prove.

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  2. The video at the third link also does not provide any evidence to distinguish whether ERVs arose from retroviruses OR VICE VERSA. As to the 8 reasons you suggest yourself... (My reply is under each of your reasons)

    1) There is no evidence for them being originally poofed-or-designed-in elements. A basic guiding principle of science is that of parsimony. You do not complicate your ideas in the absence of evidence. It is unnecessary. And a tedious waste of time.
    My reply- parsimony is not a sufficient argument here.

    2) There is no means of distinguishing between the mooted 'VIGEs' and their re-integrated products.
    My reply- so?

    3) Whatever the answer to 2), their products still appear in corresponding loci in related species, and still force us to conclude common ancestry for the reasons already explained at length in this FAQ.
    My reply- No, they could have been created in those positions.

    4) Why would a god or other "intelligent designer'" employ such a hit-and-miss method of distributing copies of genetic material, for all intents and purposes at random in the genomes they created, more often than not causing damage?
    My reply- the whole idea of VIGEs is to allow for the kind of variation (often happening FAR MORE QUICKLY than random evolution could manage) that we ACTUALLY SEE in all kinds of living things.

    5) Why are none of these so-called "VIGEs" still active in the population?
    My reply- why do you say they are not active? Variation within kinds still occurs.

    6) Why couldn't this god or other "intelligent" designer just poof or design in what they wanted in the first place?
    My reply- this way is better. It provides for adaptation to new environments for example.

    7) The whole idea of the utility of "variation inducing genetic elements" is highly derivative of the principle of the natural selection of undirected heritable variations. Either this principle is valid, or it is not. You can't have it both ways.
    My reply- Natural Selection is fact. But Natural Selection is NOT Evolution (in the protozoa to people sense).
    😎 According to creationist lore, "information cannot increase in the genome", yet here they are, proposing a mechanism to do just that.
    My reply- No. The evidence indicates that genomic information cannot (statistically speaking) increase THROUGH SIMPLE RANDOM MUTATIONS.

    My conclusion- ERVs are not a slam-dunk for Evolution. ERV's (including the idea they can't be older than 50,000 years) and the irreducible complexity involved (including the four different enzymes that must all be functioning) are better explained by Intelligent Design and Supernatural Creation.

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